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Still fighting depression while on medication?

Research studies are enrolling adults in Texas who are still experiencing significant depression symptoms despite taking an antidepressant.

See if you qualify

About

If you have been on an antidepressant for a while and still feel like depression is making daily life hard, this research study may be worth a look. Researchers in Austin, Texas are recruiting for clinical studies looking at whether an investigational drug, added on top of your current antidepressant, can provide more relief. You would not stop your current medication. You would keep taking it at the same dose the whole time, and the investigational drug would be added alongside it. Studies are open to adults in Texas who have a diagnosis of major depressive disorder (moderate or severe) or persistent depressive disorder and whose current antidepressant has not given them enough relief. The screener below takes just a few minutes and is the first step to finding out if this study is a fit for you.

Quick facts

Study Location
Study visits take place at research sites in Texas
Keep Your Medication
You continue your existing antidepressant at the same dose throughout the entire study
Investigational Add-On
An investigational drug is added alongside your current antidepressant — you do not switch treatments
Phase III Studies
Phase III clinical studies of an investigational add-on drug

What to expect

  • Complete a short online screener to see if you meet the basic requirements
  • Speak with the study team to review your medical history and ask any questions you have before committing to anything
  • Attend scheduled in-person study visits at a Texas research site
  • Continue taking your current antidepressant at your existing dose for the full length of the study
  • Take an investigational drug — or placebo — added on top of your current antidepressant, depending on which group you are assigned to
  • Complete regular check-ins and assessments with the study team to track how you are doing
Who qualifies
  • You are 18 years old or older
  • You have been diagnosed with major depressive disorder (moderate or severe) or persistent depressive disorder
  • You are currently taking an oral antidepressant and have been for at least 8 weeks
  • Your depression symptoms are still significantly affecting your daily life even on your current medication
  • You are willing to keep taking your current antidepressant at the same dose for the length of the study
  • You live in Texas or can travel to a Texas research site for study visits

Additional medical criteria apply. The study team will review your full eligibility with you — completing the screener is just the first step. Individuals shown are models, not actual patients.

Ready?

Research like this helps build a clearer picture of what works for people whose depression has not responded enough to antidepressants alone.

See If You Qualify

See if you qualify

Answer a few short questions to find out if this study may be a fit for you.

Check your eligibility →
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